Omnia mea mecum porto

IMG_2718.jpg

People

 
D3S_6810.jpg

IVAYLO (IVO) IVANOV

ASSISTANT PROFESSOR

Dr. Ivanov obtained a B.Sc. in Biotechnology and M.Sc. in Molecular Biology from Sofia University in his native Bulgaria. He obtained his Ph.D. in Cell and Molecular Biology from The University of Alabama at Birmingham. He performed his thesis work on generation of antibody repertoire diversity in the laboratory of Dr. Harry Schroeder, Jr., at the Department of Microbiology at UAB. He then joined the laboratory of Dr. Dan Littman at the Skirball Institute at New York University as a Postdoctoral Fellow in mucosal immunology. In 2011, he became an Assistant Professor at Columbia University.

IMG_2744.jpg

LEANDRO ARAUJO

POSTDOCTORAL SCIENTIST

Leandro obtained his Ph.D. in microbiology and immunology from Universidade Federal de Sao Paulo in 2014. His thesis in in the laboratory of Dr. Alexandre Basso investigated the role of the sympathetic nervous system in autoimmune inflammation. He joined the Ivanov lab in 2017 to investigate the molecular mechanisms of SFB interaction with the host.

Selected publications:

Guereschi, M.G.; Araujo, L.P.; Maricato, J.T.; Takenaka, M.C.; Nascimento, V.M.; Vivanco, B.C.; Reis, V.O.; Keller, A.C.; Brum, P.C.; Basso, A.S. Beta2-adrenergic receptor signaling in CD4 + Foxp3 + regulatory T cells enhances their suppressive function in a PKA-dependent manner. European Journal of Immunology, 43: 1001 - 1012, 2013

Takenaka, M. C.; Araujo, L.P; Terzi Maricato, J.; Nascimento, V. M.; Guereschi, M. G.; Rezende, R. M.; Quintana, F. J.; Basso, A. S. Norepinephrine Controls Effector T Cell Differentiation through 2-Adrenergic Receptor-Mediated Inhibition of NF-kB and AP-1 in Dendritic Cells. The Journal of Immunology, 196:637 - 644, 2015

IMG_2748.jpg

KOICHIRO IRIE

POSTDOCTORAL SCIENTIST

Dr. Irie obtained a D.D.S. in 2006 and Ph.D. in 2011 from Okayama University School of Medicine. He joined the Ivanov Lab in 2017 and is currently working on the role of innate lymphoid cells in mucosal immunity.

Selected Publications:

Irie K, Novince CM, Darveau RP. Impact of the oral commensal flora on alveolar bone homeostasis. J Dent Res 2014;93:801-806

Irie K, Tomofuji T, Ekuni D, Morita M, Shimazaki Y, Darveau RP. Impact of oral commensal bacteria on degradation of periodontal connective tissue in mice. J Periodontol 2015;86:899-905

IMG_2745.jpg

MADELINE EDWARDS

GRADUATE STUDENT - MICROBIOLOGY AND IMMUNOLOGY

Madeline received a B.S. degree in Molecular, Cellular and Developmental Biology magna cum laude from the University of Colorado at Boulder in 2016. She joined the Ivanov lab in 2018 and is currently working on identifying immunomodulatory microbes from the gut microbiota.

YOSHINAGA KAWANO

POSTDOCTORAL FELLOW

Dr. Kawano received his M.D. and Ph.D. from Keio University School of Medicine in 2013. His thesis focused on the role of intestinal macrophages in metabolic syndrome and type 2 diabetes. He joined the Ivanov lab in 2018 to work on immuno-metabolism as related to intestinal immunity.

Selected Publications:

Kawano Y, Nakae J, Watanabe N, Kikuchi T, Tateya S, Tamori Y, Kaneko M, Abe T, Onodera M, Itoh H. Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-dependent Manner. Cell Metabolism, 24:2016, 295-310

Kawano Y, Nakae J, Watanabe N, Fujisaka S, Iskandar K, Sekioka R, Hayashi Y, Tobe K, Kasuga M, Noda T, Yoshimura A, Onodera M, Itoh H. Loss of PDK1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance. Diabetes 61: 2012. 1935-48

IMG_3052.JPG

LEONIE BROCKMANN

POSTDOCTORAL SCIENTIST

Leonie obtained her Ph.D. from the University of Hamburg in 2016 under the mentorship of Dr. Samuel Huber. There she studied the role of IL-10 receptor signaling in differentiation of Tr1 cells. She joined the Ivanov Lab in 2018 to study differentiation pathways for mucosal Th17 cells.

Selected Publications:

Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herker J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S. IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo. Journal of Immunology. 2017, 198(3):1130

Brockmann L, Giannou AD, Gagliani N, Huber S. Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis.Int J Mol Sci. 2017 May 11;18(5)



IMG_3052.JPG

CAROLYN LEE

LAB MANAGER

Carolyn joined the Ivanov Lab in 2011 as a lab manager. She is a graduate of Columbia College.